Last season the women's basketball team only mustered 26 points in a 40 point rout by Villanova.
In their home opener this year, the Quakers bounced back to nearly pull off a stunning upset.
Instead, Sioban O'Connor hit a huge three-pointer with 36 seconds left to propel Villanova to a 45-43 victory.
The Quakers also lost sophomore Kim Adams, an Ivy League All-Rookie team selection and the team's second leading scorer last season, after she decided to leave the team for personal reasons.
After leading for much of the second half, the Quakers had three chances to tie the game in the final seconds, but freshman Tyler Cumbo's shot with 6 seconds left didn't fall.
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