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Wednesday, Jan. 14, 2026
The Daily Pennsylvanian

News brief: Penn doctors link Lou Gehrig's, dementia

Researchers at Penn's School of Medicine have discovered a major protein related to Lou Gehrig's disease and a type of dementia.

Lou Gehrig's disease, formally known as amyotrophic lateral sclerosis, causes degeneration of the brain.

Penn researchers found that patients with this disease and a type of dementia - marked by the degeneration of the brain's frontal lobe - abnormally store up a specific protein.

This discovery provides the first connection between the two diseases, though scientists have long suspected that such a link exists.

Researchers say the uncovering of the protein will open up opportunities for examining why patients with these diseases develop certain behavioral changes.